Blar i forfatter "Hanssen, Anne Merethe"

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    • Culturing periprosthetic tissue in BacT/Alert® Virtuo blood culture system leads to improved and faster detection of prosthetic joint infections 

      Sanabria-Moreno, Adriana Maria; Røkeberg, Merethe E.O.; Johannessen, Mona; Sollid, Johanna U Ericson; Simonsen, Gunnar Skov; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-10)
      <i>Background</i> - Blood culture bottles (BCBs) provide a semiautomated method for culturing periprosthetic tissue specimens. A study evaluating BCBs for culturing clinical samples other than body fluids is needed before implementation into clinical practice. Our objective was to evaluate use of the BacT/Alert® Virtuo blood culture system for culturing periprosthetic tissue specimens. <p> ...

    • Exploring differentially expressed genes of Staphylococcus aureus exposed to human tonsillar cells using RNA sequencing 

      Bastakoti, Srijana; Ajayi, Clement; Julin, Kjersti; Johannessen, Mona; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel, 2023-07-12)
      Background - The nose and the throat are the most predominant colonizing sites of Staphylococcus aureus, and colonization is a risk factor for infection. Nasal colonization is well described; however, we have limited knowledge about S. aureus throat colonization. The main objective of this study was to explore differentially expressed genes (DEGs) in S. aureus throat isolate TR145 exposed to human ...

    • Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers 

      Ajayi, Clement; Åberg, Espen; Askarian, Fatemeh; Sollid, Johanna U Ericson; Johannessen, Mona; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-16)
      <p><i>Background</i>: <i>Staphylococcus aureus</i> cell wall anchored Serine Aspartate repeat containing protein D (<i>sdrD</i>) is a member of the microbial surface component recognising adhesive matrix molecules (MSCRAMMs). It is involved in the bacterial adhesion and virulence. However the extent of genetic variation in <i>S. aureus sdrD</i> gene within isolates from healthy carriers are not ...

    • Shotgun-metagenomics based prediction of antibiotic resistance and virulence determinants in Staphylococcus aureus from periprosthetic tissue on blood culture bottles 

      Sanabria-Moreno, Adriana Maria; James Peter, Jessin Janice; Hjerde, Erik; Simonsen, Gunnar Skov; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-21)
      Shotgun-metagenomics may give valuable clinical information beyond the detection of potential pathogen(s). Identification of antimicrobial resistance (AMR), virulence genes and typing directly from clinical samples has been limited due to challenges arising from incomplete genome coverage. We assessed the performance of shotgun-metagenomics on positive blood culture bottles (n = 19) with periprosthetic ...

    • Shotgun-Metagenomics on Positive Blood Culture Bottles Inoculated With Prosthetic Joint Tissue: A Proof of Concept Study 

      Sanabria-Moreno, Adriana Maria; Hjerde, Erik; Johannessen, Mona; Sollid, Johanna U Ericson; Simonsen, Gunnar Skov; Hanssen, Anne Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-17)
      Clinical metagenomics is actively moving from research to clinical laboratories. It has the potential to change the microbial diagnosis of infectious diseases, especially when detection and identification of pathogens can be challenging, such as in prosthetic joint infection (PJI). The application of metagenomic sequencing to periprosthetic joint tissue (PJT) specimens is often challenged by low ...

    • Social network analysis of Staphylococcus aureus carriage in a general youth population 

      Stensen, Dina Benedicte Berg; Cañadas, Rafael A. Nozal; Småbrekke, Lars; Olsen, Karina; Nielsen, Christopher Sivert; Svendsen, Kristian; Hanssen, Anne Merethe; Ericson, Johanna U; Simonsen, Gunnar Skov; Bongo, Lars Ailo; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-31)
      Objectives Staphylococcus aureus carriage increases infection risk. We used social network analysis to evaluate whether contacts have the same S. aureus genotype indicating direct transmission, or whether contagiousness is an indirect effect of contacts sharing the same lifestyle or characteristics. Methods The Fit Futures 1 study collected data on social contact among 1038 high school students. ...